The Role of #Fibrin in #Parkinson’s #Disease #Serrscor NK

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Parkinson’s disease is an irreversible nervous system disorder that primarily affects musculo-skeletal movement. While the progressive disorder can cause stiffness and slow movements, signs and symptoms vary greatly among patients.

Common symptoms include: 
Tremors
Slowed Movement
Rigid Muscles
Impaired balance
Impaired Posture 
Speech changes

Parkinson’s disease is caused by the gradual breakdown of brain cells called neurons. The loss of neurons leads to a decrease in dopamine levels, leading to abnormal brain activity. Only 5% of Parkinson’s cases occur before the age of 40, with incidence increasing with age. A majority of cases seem to be sporadic and of unknown origin – however, like most diseases, there is a significant genetic component.

Recent theories about the causes of Parkinson’s disease are based on abnormal fibrin production and deposition in the brain. Also known as the “amyloid hypothesis,” researchers have been looking at the role of abnormal protein aggregation in Parkinson’s and other neurodegenerative disorders, like Alzheimer’s disease. There seems to be a correlation between fibrin deposits and brain tissue degeneration, suggesting that the fibrin contributes to cellular death in these diseases. Similar to Alzheimer’s disease and Huntington’s disease, Parkinson’s disease involves the mis-folding of a specific protein, eventually leading to fibrin deposits.

There are several theories as to the underlying cause of Parkinson’s, from oxidative damage to environmental toxins – but the latest research seeks to understand why the dopamine-containing neurons are affected so greatly. In fact, by the time a Parkinson’s patient presents with symptoms, about 70% of the dopamine-containing neurons have already been lost. Current therapies aim to address dopamine deficiencies, but future therapies seek to address the prevention of neuron degeneration (cellular death of the brain cells).

Although systemic enzymes are implicated for the treatment of Alzheimer’s disease, their use in similar neurodegenerative diseases has yet to be studied. Specifically nattokinase, which has been shown to directly dissolve the aggregated protein found in Alzheimer’s disease, may be an option available to those suffering from Parkinson’s disease.

 Nattokinase is a natural systemic enzyme that helps to decrease fibrin levels in the blood. Nattokinase is also able to reach areas where fibrin has already accumulated – helping to restore blood flow and inhibiting cellular death due to oxidative damage. Perhaps the most promising aspect of systemic enzyme therapy is its ability to be used concurrently with other medications. The only restriction is upon the use of nattokinase, which should be discussed with a doctor prior to adding it to a regimen with prescription blood thinners. However, it should be noted that systemic enzymes do not cause adverse side effects or drug-drug/drug-nutrient interactions.

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Systemic Enzymes for #Parkinson's #Excellacor

 

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The Common Cause of Parkinson’s
By William Wong ND, PhD, Member World Sports Medicine Hall of Fame

The road to discovery is long and winding. Some of its paths lead to dead ends, some of its paths curve round and round until they lead to truth. The paths trod by those seeking the cause and then a cure for the ills that effect the brain are no different.

In the search for the root cause of Alzheimer's many degenerative changes in the brain of its victims have come to light: protein cross linking short circuiting nerve transmission, aluminum shards in DNA strands, decrease in neurotransmitters, the shrinking of the brain due to loss of its fat content (the brain is 70% cholesterol), but all of these factors are the results of the condition and not its direct cause. It is now known that moderate inflammation, not enough to be called Enchaphilitis, but enough to have been medically detected, is the root cause of the condition. 

 

With Parkinson’s patients a part of the brain called the Substancia Nigra dies off. This vital part of the brain makes a substance called Dopamine. It is dopamine that connects the brain to the body. As dopamine levels decrease while the Substancia Nigra dies off, slowly the control the brain exerts over the body diminishes. So essential is dopamine that doctors can tell a “pre morbid” (just before death) condition by monitoring blood levels of dopamine. Three days after the last drop of dopamine is made by the brain the person dies! A link between sub clinical brain inflammation and Parkinson’s has just been found!

Serracor-NK for #Fibromyalgia - a disorder of chronic widespread pain

 

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Fibromyalgia is a disorder of chronic, widespread pain and tenderness (see the image below). It typically presents in young or middle-aged women but can affect patients of either sex and at any age.

 

Tender points in fibromyalgia.

Signs and symptoms

Fibromyalgia is a syndrome that consists of the following signs and symptoms

• Persistent (≥3 mo) widespread pain (pain/tenderness on both sides of the body, above and below the waist, including the axial spine [usually the paraspinus, scapular, and trapezius muscles])
• Stiffness
• Fatigue; disrupted and unrefreshing sleep
• Cognitive difficulties
• Multiple other unexplained symptoms, anxiety and/or depression, and functional impairment of activities of daily living (ADLs)

Diagnosis

Fibromyalgia is a diagnosis of exclusion and patients must be thoroughly evaluated for the presence of other disorders that could be the cause of symptoms before a diagnosis of fibromyalgia is made. The clinical assessment may reveal objective evidence for a discrete or comorbid illness, such as the following:

• Hypothyroidism
• Rheumatoid arthritis
• Systemic lupus erythematosus
• Polymyalgia rheumatic
• Other inflammatory or autoimmune disorders
• Serious cardiac conditions in those with chest pain, dyspnea, and palpitations

• Social Support Questionnaire
• Sickness Impact Profile
• Multidimensional Pain Inventory

See Workup for more detail.

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Management

There is no cure for fibromyalgia, but education, lifestyle changes, and proper medications can help the individual to regain control and achieve significant improvement.
Models of pain behavior that interrelate biologic, cognitive, emotional, and behavioral variables form the basis for cognitive-behavioral and operant behavioral approaches to adult pain management. Fibromyalgia in children responds to a combination of psychotherapy, exercise, relaxation techniques, and education. Pharmacotherapy is generally not indicated in children.
Nonpharmacotherapy

• Diet (eg, promote good nutrition, vitamin supplementation, bone health, weight loss)
• Stress management
• Aerobic exercise (eg, low-impact aerobics, walking, water aerobics, stationary bicycle)
• Sleep therapy (eg, education/instruction on sleep hygiene)
• Psychologic/behavioral therapy (eg, cognitive-behavioral, operant-behavioral)

Other agents used in fibromyalgia may include the following:

• Vitamins and minerals
• Malic acid and magnesium combination
• Antioxidants
• Amino acids
• Herbs and supplements

•  
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Floracor 5 ways you are harming your gut bacteria

 

5 ways you are harming your gut bacteria

Our society has adopted some very unhealthy activities and lifestyles that affect our microbes in a variety of ways. Most are difficult to avoid, but it's critical to spread awareness if we want to protect our microbiome.

A microbiota is an "ecological community of commensal, symbiotic and pathogenic microorganisms" found in and on all multi cellular organisms studied to date from plants to animals. A microbiota includes bacteria, archaea, protists, fungi and viruses. Here are just a few easy ways you can understand how bacteria works.

  

Wine and beer. Alcohol consumption can alter your microbial balance

 

Sweets. Processed sugars can feed potentially unhealthy bacteria

Poor sleep. This can lead to subtle changes in your microbial makeup

Antibiotics. These kill both good and bad bacteria.

Tap water. Chlorine in tap water kills both good and bad bacteria.

These are just a few of the most common culprits. If any of these apply to you, it may be time to look for a probiotic.

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#Cystic #Fibrosis Conference #Serracor-NK #NACFC

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What is cystic fibrosis?

Cystic fibrosis (CF) is a genetic condition, which means that it is something you are born with. CF is known to cause your lungs to produce extra-thick, sticky mucus. This mucus builds up and clogs your airways.

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What makes healthy lungs "healthy"?

The lungs naturally produce a thin layer of mucus that helps protect the airways from dangerous bacteria that can cause infections.

How are lungs affected by CF different?

For people living with CF, the mucus in the lungs is thicker than normal. This thick mucus can build up in the airways, allowing germs to thrive and become a source of infection and inflammation that can lead to decreased lung function.

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Benefits of #Serrapeptase

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In the U.S., Serrapeptase is classified as a dietary supplement. Serrapeptase is used for painful conditions including back pain, osteoarthritis, rheumatoid arthritis, osteoporosis, fibromyalgia, carpel tunnel syndrome, migraine headache, and tension headache.

What foods contain serrapeptase?

While there are no foods that actually contain serrapeptase, doctors who recommend this enzyme suggest that people to stick to a mainly Mediterranean diet. Eat organic meats, fish and poultry. Beans, nuts, fruit and vegetables should also be incorporated. Whole foods and raw foods are the best.

 Serrapeptase is thought to work in three ways:

1. It may reduce inflammation by thinning the fluids formed from injury, and facilitating the fluid’s drainage. This in turn, also speeds tissue repair.
   
2. It may help alleviate pain by inhibiting the release of pain-inducing amines called bradykinin.
3. It may enhance cardiovascular health by breaking down the protein by-products of blood coagulation called fibrin. Conveniently, Serrapeptase is able to dissolve the fibrin and other dead or damaged tissue without harming living tissue. This could enable the dissolution of atherosclerotic plaques without causing any harm to the inside of the arteries. 
   

Serrapeptase has been used in Europe and Asia for over 25 years. Because the enzyme digests or dissolves all nonliving tissue, including blood clots, cysts and arterial plaque, it is used to treat a variety of conditions, including sprains and torn ligaments, postoperative swelling, venous thrombosis (clots in the legs), ear, nose and throat infections and atherosclerosis.

Abroad, Serrapeptase is marketed under a variety of names including, DanzenTM, AniflazymTM, and SerraZymeTM. In the United States, it has been used and marketed as Serrapeptase since 1997. A pain-reliever and anti-inflammatory supplement that has anti-clotting activities without the risk of stomach bleeding? Sounds too good to be true? Let’s look at the research.

 

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Digestive Enzymes & Probiotics #Floracor & #Digest-GI

 

Digestive enzymes improve the function of your digestive system and make you feel better after eating a meal. The majority of digestive support supplements contain a blend of enzymes, but with so many ingredients on every label, it can be hard to choose the right supplement for your needs.

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Below are three highly effective digestive enzymes to consider when choosing a supplement.

1. Papaya
Papayas are a rich source of valuable proteolytic enzymes, such as papain, chymopapain, caricain and glycyl endopeptidase, that can greatly aid in the digestive process. The enzyme papain is one of the most effective at breaking down meat and other proteins, comparable to the enzyme pepsin that we produce in our pancreas.

In fact, papain is often considered a more effective enzyme than pepsin. Eating the papaya enzyme papain in a meal containing meat can significantly speed up its digestion. It may also help with the breakdown of other troublesome proteins, such as the gluten in wheat and the casein in milk, that are often implicated in digestive problems.

2. Bromelain
Bromelain is an enzyme found in pineapple juice and in the pineapple stem and is known to improve digestion. Used for reducing swelling and inflammation, bromelain has been shown to treat a bowel condition that includes swelling and ulcers. Often used in digestive support products, bromelain can also help improve the absorption of antibiotics. Bromelain seems to cause the body to produce substances that fight pain and inflammation.

3. Hydrochloric Acid (HCL)
Hydrochloric acid, also called HCL, is one of the many chemicals released in our stomach when we eat a meal. The role of hydrochloric acid in the stomach, along with the other gastric juices, is to break down foods and cause the release of enzymes that further aid digestion. HCl also protects the body from illness by killing pathogens commonly found in foods.

HCL supplements can aid the stomach’s acid to destroy harmful bacteria as well as relieve the symptoms of heartburn. Low stomach acid causes indigestion, gas, bloating, acid reflux, constipation, and diarrhea.

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